• Researchers at CECTA and DECYTAL at Universidad de Santiago successfully participated in two important scientific gatherings. They were the only Chileans participating in the 27^th International Conference on Yeast Genetics and Molecular Biology and the 02^nd International Specialized Symposium of Yeasts, held in the Italian cities of Levico and Perugia, respectively. Dr Verónica García Mena, Dr Claire Brice, Dr Claudio Martínez Fernández and Dr Francisco Cubillos Riffo presented their works at these conferences.

   

  Researchers at the Food Science and Technology Research Center (CECTA, in Spanish) and the Department of Food Science and Technology (DECYTAL, in Spanish) of Universidad de Santiago were the only Chilean representatives in two important scientific activities held in September, in Italy.

  The team led by Dr Claudio Martínez Fernández and made up of Dr Francisco Cubillos Riffo, Dr Verónica García Mena, and Dr Claire Brice presented the results of different studies conducted at the Applied Biotechnology and Microbiology Laboratory.

  The researchers participated in the 27^th International Conference on Yeast Genetics and Molecular Biology, held between September 06^th and 12^th, in Levico, and the 02^nd International Specialized Symposium of Yeasts, held between September 13^th and 17^th in Perugia, Italy.

  Strengthening links

  The director of CECTA, Dr Claudio Martínez, who is currently on a scientific-cultural exchange at the Instituto de Agroquímica y Tecnología de Alimentos (IATA, in Spanish) in Valencia, Spain, explained that the importance of these conferences lies on the possibility of “Strengthening links with the best researchers in this field worldwide, strengthening joint projects and opening opportunities to new collaborations and projects, as well as evaluating the level and the significance of what we are doing in Chile, that it is certainly very good at an international level.”

  For example, the team of CECTA is working on an international collaboration project with researchers at the IATA that also involves Argentinean researchers. And there is another international project with a French team that also participated in these conferences. This team is collaborating with a Fondecyt postdoctoral project and Dr Claire Brice is in charge of the last phase of this study.

  It is worth to mention that CECTA researchers were the only Chilean representatives in both conferences. According to professor Martínez, this was a surprise. And they were more surprised when they realized that, at a Latin American level, there were a few researchers from Argentina, Brazil and Uruguay. “This places us in a leading position at a national level and allows us to strengthen links with Latin American experts in this field to promote local and regional development,” he said.

  Leaders in yeast studies

  Yeasts were the common denominator in the conferences in which Universidad de Santiago researchers participated. Our university is leader in the area of yeast biotechnology in the country. “In this regard, the contributions made by our institution have turned into products (some of them have already been transferred to the productive sector in Chile and abroad) and specialized human resource training and have generated a worldwide renowned group of experts,” he concluded.

   

  Translated by Marcela Contreras

• With the funding of a Fondecyt Postdoctoral Project 2016, Dr Baptiste Darbois, professor at the Faculty of Science of Universidad de Santiago, will be able to accurately determine how lizards move in granular soils in order to produce results that allow to create a robot able to move easily in different types of soil.

With the funding of a Fondecyt Postdoctoral Project 2016, Dr Baptiste Darbois, professor at the Faculty of Science of Universidad de Santiago, will be able to accurately determine how lizards move in granular soils in order to produce results that allow to create a robot able to move easily in different types of soil. This would mean a significant contribution to robotics.

Based on previous research that found that once lizards dive in the sand, they move by wriggling their bodies and not by using their legs, Dr Darbois will study the interaction between a vibrating elastic structure and the granular environment.

The Fondecyt Postdoctoral project (3160167) is called “Locomoción ondulatoria de nadadores suaves dentro de los medios granulares.”

Experimental challenge

The experimental challenge of the study is to control the movement of grains and the forces they undergo when lizards move. This would help to establish guidelines for developing robots able to adapt themselves to different environments. The way of moving of different animals has inspired engineers in this field.

“We expect the compression produced by lizards’ undulating movements in the desert’s sub-surface to help us to develop efficient robots by incorporating this mechanism,” Dr Darbois explained.

Likewise, professor Darbois intends to develop, in the long term, a robot based on the best features lizards show when moving in a granular environment.

“Through this project, we expect to define the optimal conditions: the dimensions, elasticity, frequency and amplitude of vibrations to move forward in waves through a granular environment,” the researcher said.

The relationship between lizards and the development of robots is not odd; on the contrary, it can benefit technological development and improve people´s quality of life. For example, it can be used in critical situations.

“With regard to its applications, developing robots able to efficiently move in granular environments could help to detect anti-personnel mines in the deserts and find people trapped under avalanches,” Dr Darbois concluded.

Translated by Marcela Contreras

• A research team at the Faculty of Chemistry and Biology led by Dr Claudia Ortiz Calderón developed a device based on Chilean brown algae and pumice stone, which is able to adsorb copper from copper-bearing solutions produced by mining industry.

A research team at the Faculty of Chemistry and Biology led by Dr Claudia Ortiz Calderón developed a device based on Chilean brown algae and pumice stone, which is able to adsorb copper from copper-bearing solutions produced by mining industry.

Dr Ortiz, who is in charge of the Laboratory of Vegetable Biochemistry and Phytoremediation of the university, says that this study is part of the research that they usually conduct on the use of plants for environmental remediation.

Using this new device, it is possible to adsorb copper from copper-bearing streams to recover ions and send them back to the mining process, and clean the waters to use them again. Dr Ortiz says that they are already studying the effectiveness of the bio-filter with other metals, what could attract the interest of different companies.

Basically, the bio-filter is a vertical-flow column that contains three types of brown algae – which are very common in the Chilean coast- and pumice stone arranged in a way that is able to capture copper.

“First, we collect the algae and then, after washing, drying, chopping and screening them to a specific size, we package them together with pumicite or pumice stone that prevents the algae from getting compressed,” Dr Ortiz says.

She emphasizes that, in order no produce the bio-filter, they do not require to collect living biomass or to harvest algae. As they use waste algae and do not pre-treat the biomass, the bio-filter has a low cost of production. 

Patent request

The project started in 2012 and was funded by Corfo (the Chilean Economic Development Agent). It is currently at a protection stage after filing a patent request for the packaging system.

The next step is to continue with the analyses to determine the effectiveness of the bio-filter with other metals.

“We know that the bio-filter works very well for copper and we have also tested other equivalent cations, like zinc, cobalt and cadmium, and they have usually worked quite well too,” Dr Ortiz says.

“Thus, companies or industrial processes generating these elements which are interested in removing or recycling them could also be interested in the filter.”

In this context, the Canadian company Good Harbor that supported the project by conducting the hydraulic study of the columns has already expressed its interest in acquiring the rights of this new product.

Translated by Marcela Contreras

• The National Institute of Industrial Property recognized Universidad de Santiago as the third Chilean university with the highest number of invention patent requests that seek to contribute to the country development in fields like chemistry and biology, engineering and technology. Maximiliano Santa Cruz, Inapi’s National Director and Óscar Bustos, Vice President of Research, Development and Innovation of Universidad de Santiago,   encouraged the University community to continue constantly producing industrial innovations to contribute to society.

On April 25th, in the context of the World Intellectual Property Day, our University was recognized as the third best national institution in requesting invention patents during 2013.

The National Institute of Industrial Property (Inapi, in Spanish)- an agency responsible to the Ministry of Economy in charge of registering, managing and promoting industrial property rights in Chile- granted our University an award in a ceremony led by Maximiliano Santa Cruz, Inapi´s National Director.

During the activity that took place at Inapi’s building, Santa Cruz highlighted the important role played by our University in producing creative innovations that contribute to our country’s development.

“Universidad de Santiago de Chile is absolutely essential to our patenting system. It has always been in the highest positions at the patent request ranking and this is not a coincidence: it is the result of serious intellectual property policies,” Inapi’s director said.

For Maximiliano Santa Cruz, our University’s interest in industrial property “is a powerful signal to its researchers, professors and innovators, in general.”

“I ask Universidad de Santiago’s innovators to continue creating new things and using the patenting system for it is a powerful tool to protect intellectual property,” he added.

Dr. Óscar Bustos, Vice President of Research, Development and Innovation (Vridei, in Spanish) of our University, who received Inapi´s award, showed himself very pleased with the position in the ranking at a national level.

“We are very satisfied with our exceptional position among the institutions that request for invention patents (…) We would have been happy to keep the second place like we did last year, but being among the main institutions that file patents requests in Chile is excellent news indeed,” Dr. Bustos said.

Pontifica Universidad Católica was at the first place in the patent request ranking while Universidad de Concepción was at the second place.

Finally, Vice President Bustos said that the high position of our University in the ranking reflects that “our researchers have become aware that not only scientific publications are important for our country: developing specific technological projects in key areas for Chile is important too.”

According to data provided by the Department of Technology Transfer of our University, during 2013, this state and public institution filed 11 invention patent requests in Chile, and at the same time, it filed other 42 requests with foreign agencies in charge of registering industrial inventions.

Translated by Marcela Contreras
 

• For the second consecutive year, our  University was positioned in the third place of the largest national patent requests prepared by the National Industrial Property Institute (INAPI,  in Spanish). Dr. Louis Magne,  director of the Department of Technology Management, attended the awards ceremony  and he highlighted the efforts of the University to generate technological innovations.

Our University has managed to gradually increase the protection of intellectual property of the technologies  generated through its research and development. In 2011 it presented a total of 28 requests  at national and  international levels and through the Cooperation Treaty about Patenting Matters (PCT, in Spanish).

The number of nine national patent records required in 2011, helped to put the University in third place, according to the "INAPI Report 2012". The leader of this ranking was Universidad de  Concepción and P. Pontificia Universidad Católica, with a total number of thirteen requests for inventions each.

The award ceremony for this important achievement was held last Thursday in the new premises of INAPI and was chaired by Tomás Flores the Vice Secretary of Economics, and Maximiliano Santa Cruz, INAPI director.  Dr. Louis Magne, director of the Department of Technology Management from the office of Research and Development attended the ceremony and  represented our University. He  noted that patenting is a priority for the institution.

"The University has an important increase of the research that has  potential for new businesses, and this has allowed  the  identification of the results that might get a patent and which are the basis of innovative technologies that could be transferred to the productive sector," he said.

Throughout its history, the  Universidad de Santiago de Chile has presented 63 requests  for national patents. At the international level, it has presented 50 requests  in various countries, mostly in the United States. Of the total applications, 28 patents have been given, eleven  in Chilean territory, three in the U.S. and the rest in other countries.

"We are currently working to achieve that these patents generate licenses and then royalties, meeting  the challenge that Chile has about becoming a generator of technology," Magne explained.

What is the meaning of patenting?

A patent is an exclusive right granted by the State for the protection of an invention, so it recognizes and guarantees the exclusive commercial exploitation for the holder of the invention, thus preventing others from appropriating the benefits involved in its exploitation.

Obtaining these patents in the University is paramount as it demonstrates the ability to generate appropriable knowledge, and states the basis of technological products that have a future to contribute to the country and become  part of  the national and international markets.

To achieve this, the Technology Management Department is responsible for encouraging researchers to conduct applied research projects whose results are evaluated in its appropriability and evaluated for their further development, until the patent is generated.

The patents that are requested belong to the University, with the recognition of the authorship  for the inventors. If the invention is commercialized, 50 percent is for the group of researchers that  generates the patent and the remaining 50 percent for the University.

• The motion patterns typical of volcanoes can be predicted with a high rate of effectiveness as of data sent from the slopes of the Llaima Volcano in La Araucanía Region. This has been possible thanks to the work by Dr. Max Chacón, professor at the Department of Informatics Engineering of Universidad de Santiago, who developed a software program for this purpose. “In Chile, it is essential to increase the knowledge on volcanoes. In this way, we will be able to face emergency situations like eruptions, and even predict them and make timely decisions,” Dr. Chacón said.

Due to its location on the Pacific Ring of Fire, the Chilean territory has the second largest volcanic chain in the world, with more than 2,000 volcanoes, many of them located in the southern part of the country. Although they are considered among the most active volcanoes in Latin America, only 43 of them are being monitored. The main concern about these geological structures is their potential for eruptions and their seismic activity is a key factor in prevention. 

Researchers of Universidad de Santiago, Universidad de La Frontera, and the Southern Andean Volcano Observatory, Ovdas by its acronym in Spanish, conducted the study “Pattern recognition applied to seismic signals from the Llaima Volcano: an analysis of the events’ features”, which is available in the Journal of Volcanology and Geothermal Research.

According to Dr. Max Chacón, professor at the Department of Informatics Engineering of Universidad de Santiago and one of the developers of the program, “Based on the machine learning approach, we developed a piece of software that identifies the type of the seismic signal as of data sent by sensors located on the slopes of the volcano,” with an 80% accuracy in the Llaima Volcano.

“Volcano seismic signals are not related to the earthquakes typical of tectonic plate collisions, as one could deduce from a first interpretation of these phenomena. These movements are specific to volcanoes and they are caused by their distinctive features, like their activity, magma movement, gas movement, stiffness of components, etc.

Previously, the research team had studied the Villarrica Volcano, detecting the existence of three characteristic seismic event patterns: the LP (Long Period) event, which is related to the pressure of gas and other fluids in the conduit; the Tremor, which is related to changes in gas and magma densities; and lastly, the VT (Volcano Tectonic) event, which is associated to the fracture of the solid parts of the volcano or the conduits.

The researchers used the program again in a study on the Llaima Volcano, but they also tried to identify the features of data sent by the sensors in the volcano. Among these data, the amplitude, frequency and phase of the signals, and the way in which they appear together in each seismic signal, were particularly considered.

“With this, we tried to give more information to volcanologists, so that they could identify the signals more easily, also analyzing the way in which these features appeared in seismic events,” Dr. Chacón, an expert in system models, said.

According to Dr. Chacón, one of the most interesting conclusions was the similarity of the results in the two volcanoes, what contradicts the current idea that each volcano has unique seismic movements. The researcher says that for now, the hypothesis is that the similarity is due to the proximity between the two volcanoes; however, this has not been proved.

For the above, there are two potential steps to follow in the context of this research. First, a comparative study on these volcanoes to measure the exact differences between them; and second, the improvement of the program with the purpose of detecting the correlations between these seismic signals at the moment of the eruption.

“In Chile, we live with many volcanoes, so it is essential to increase the knowledge about them. The more we know, the better we will be able to face emergency situations like eruptions, and even predict them and make timely decisions,” Dr. Chacón said.


Translated by Marcela Contreras

• The National Institute of Industrial Property recognized Universidad de Santiago as the second Chilean university at filing the highest number of patent applications in 2014. “Chile has a scientific tradition that places the country at the forefront of the Latin American productivity, and numbers reflect this fact, like the second place reached by Universidad de Santiago (last year).” The award ceremony was held in the context of the World Intellectual Property Day.

Once again, Universidad de Santiago was among the three most outstanding universities in the patent category- a category related to the rights given by the Chilean State to an inventor for the development of a new technology- in the annual award ceremony organized by the National Institute of Industrial Property (Inapi). 

The ceremony was held at Patio Los Naranjos of Universidad de Santiago and it was headed by Katia Trusich, Under Secretary of Economy, Development and Tourism, and Inapi’s NationalDirector, Maximiliano Santa Cruz. The Under Secretary said that last year was a consolidation period for Inapi. And she added that the challenge now is to set out a long-term strategy to allow “the development of industrial property considering the specific requirements of the country with regards to productive development, innovation and business ventures.”

For his part, Inapi’s National Director emphasized that our institution has a very important commitment with regards to patent application processing. “In Chile, universities are doing a good job at patenting and, if they are considered all together, in 2014 they almost doubled the number of patent applications filed, in comparison to the previous year.”

Besides congratulating Universidad de Santiago for its great work and interest in patent matters, she said that our University “is making big efforts to obtain patents, something that should be continued and promoted. Generating new knowledge through scientific activity at universities is an essential tool for economic, social and cultural development.”

“Chile has a scientific tradition that places the country at the forefront of the Latin American productivity, and numbers reflect this fact, like the second place reached by Universidad de Santiago in the national patent application ranking of 2014”, Maximiliano Santa Cruz said.

Luis Magne, Head of the Department of Technology Management of Universidad de Santiago- the unit in charge of processing patent applications of the University, among other tasks- said: “Universidad de Santiago continues to keep its spirit of technological university, so it puts an emphasis on applied research and innovation in order to contribute to the society welfare and to have an impact on Chile and the world.”

According to the information given by the Department of Technology Management, in 2014, Universidad de Santiago filed 23 new patent applications with Inapi, doubling the number of patents filed in 2013. This placed the University in the third position of the ranking that year. In addition, it filed 44 invention and protection patent applications with international agencies.

These patents are related to the fields of Sciences, Engineering, Technology, and Chemistry and Biology, and most of them belong particularly to the areas of Biotechnology, Manufacturing and Aquaculture.

Universidad de Concepción was at the first place in the patent application ranking while Pontificia Universidad Católica was at the third place.

Translated by Marcela Contreras

•  Dr Jenny Blamey, professor at the Faculty of Chemistry and Biology described the 13^th International Thermophiles Meeting as a very important opportunity for the development of research at Universidad de Santiago and in the country. Worldwide prominent figures in microbiology, molecular biology, biochemistry, genetics, biocatalysis and biotechnology, participated in the conference. This is the first time that this global meeting is held in South America and Dr Blamey was in charge of the organization.

   

  In her closing speech, Dr Jenny Blamey, professor at the Faculty of Chemistry and Biology of Universidad de Santiago, evaluated this global meeting as a very important opportunity for the development of research at Universidad de Santiago and in the country.

  Dr Blamey highlighted the scientific importance of this conference that always leaves its imprint on the research centers and the countries where it is held. This also happened in our university and it should be reflected on the country.

  During the activity, worldwide leading scientists in this field presented their top-notch studies.

  These experts in microbiology, molecular biology, biochemistry, genetics, biocatalysis and biotechnology informed about the progress in their specialities, in order to have a better understanding of thermophiles.

  The Thermophiles International Conference is a global meeting held every second year. For the first time the meeting was carried out in South America, under the general supervision of Dr Blamey, and with the support of an efficient team who coordinated different tasks for the organizing bodies: Bioscience Foundation and the Faculty of Chemistry and Biology of Universidad de Santiago.

  The program included sessions on topics like genomics and biochemical processes, keynote lectures and poster presentations.

  International experts like Dr Karl Stetter, Dr Michel Adams and Dr Juergen Wiegel met with students, researchers and Chilean and foreign scientists.

  They shared their questions and their knowledge about the last developments and potential biotechnological applications of thermophiles, which are considered key to science development in our country and the world.

  A space for discussion and proposals

  “For Universidad de Santiago de Chile, hosting and promoting this type of activity is essential, since our purpose as a public, state and complete university is to create, preserve, disseminate and apply knowledge for the welfare of society,” Dr Juan Manuel Zolezzi, President of Universidad de Santiago, said.

  The Thermophiles 2015 International Conference contributed “To our institutional essential work, as it became a space for discussion and proposals, in a multidisciplinary and pluralistic dialogue; on this occasion, in the field of extremophiles, a new important field worldwide, not only for biological sciences but also for industrial biotechnology,” he added.

  For his part, Dr Gustavo Zúñiga, Dean of the Faculty of Chemistry and Biology, highlighted the importance of having been selected to organize the activity and receive these distinguished scientists, and give the students the opportunity to ask questions and talk to them.

  Translated by Marcela Contreras

• Dr Erick Saavedra Flores, researcher at the Department of Civil Works Engineering of Universidad de Santiago de Chile, is studying new mathematical techniques to computer simulate the performance of wood at extreme ranges of deformation, cracking and ductile processes and its possible progressive collapse.

Wooden structures in a seismic country like Chile require constant inspection to check on its resistance in case of critical events such as earthquakes.

Dr Erick Saavedra Flores, researcher at the Department of Civil Works Engineering of Universidad de Santiago de Chile, is studying new mathematical techniques to computer simulate the performance of wood at extreme ranges of deformation, cracking and ductile processes and, eventually, in a progressive collapse.

Dr Saavedra explains that failures in wooden structures are divided into two groups: brittle and ductile failures. Both will determine the time before wood collapses. “Usually, structures fail abruptly, without previous notice. This type of failure is classified as ‘brittle’. However, at a local level, close to metal joints or fittings, wood fails in a “ductile” manner, i.e., it fails gradually in time. This latter type of failure is very common in very high buildings made of wood,” he says.

With the resources provided by a Fondecyt Regular project, Dr Saavedra will present a new model based on a mathematical technique called “homogenization”, which seeks to detect cracking and irreversible deformation processes at different spatial scales.

Worldwide efforts

“Achieving this goal will be a big challenge, because we require to extend the existing theory to incorporate the damage factor, i.e., degradation, loss of material stiffness and cracks into the multi-scale mechanical response of the material. In the past few years, big efforts have been made worldwide; however, predicting the mechanical performance of materials in this context remains to be a problem without a solution that is fully accepted by the scientific community,” he says.

He explains that he intends to incorporate this new material model to the advanced analysis of large-scale structures, because the big challenge posed by this goal is to computer simulate the progressive collapse of structures during seismic events.

In this regard, modeling this problem is extremely difficult as it involves extreme deformation processes, the interaction of elements that fall during the collapse process and their consequent fragmentation.

The project also considers experimental testing to validate the numerical predictions obtained during the study. Running these tests will be possible with the acquisition of a vibrating table for the Department of Civil Works Engineering.

As a final result of this study, the researcher expects to have material advanced models able to capture extreme deformation processes that allow to calculate ductility measures.

“I believe that the major impact my project may have is in the area of design and construction of buildings and large-scale structures. In the case of wood, particularly, it is possible to promote the use of radiata pine to construct tall buildings if we have a more precise knowledge of its performance during failures or eventual structural collapse,” Dr Saavedra explains. 

The study will be conducted in the context of the Fondecyt Regular project 2016 (1160691), “Advanced Modelling of Ductility and Damage in Mass Timber Structures by Computational Homogenization.”

Translated by Marcela Contreras

• Damian Clarke, Associate Professor at the Faculty of Administration and Economics of Universidad de Santiago de Chile, together with Sonia Bhalotra, Professor of Economics at the University of Essex, conducted a study that relates maternal mortality to education.

In 2015, the World Health Organization estimated that 830 women died every day at childbirth. These numbers could have been prevented with timely access to contraceptive methods and obstetric care, as a result of the policies established by the Millennium Development Goal (MDGs) and the Sustainable Development Goals (SDGs).

The goal was to reduce maternal mortality by at least 75% over a 30-year-period. In spite of the progress in this field, the MDG was not achieved; therefore, implementing new policies is urgently required.

In view of this situation, Damian Clark, PhD in Economics from the University of Oxford and Associate Professor at the Faculty of Administration and Economics of Universidad de Santiago, together with Sonia Bhalotra, Professor of Economics at the University of Essex, decided to study the reduction of maternal mortality caused by education. They conducted the study “Maternal mortality and Education,” in which they established an empirical relation between both factors.

The World Institute Development Economics Research (UNU-WIDER), in Helsinki, prepared a video that summarizes this important study in order to disseminate it worldwide through different media. 

UNU-WIDER is a unique blend of think tank, research institute, and UN agency that provides a range of services from policy advice to governments as well as freely available original research coordinated by a core group of resident and non-resident researchers and undertaken by a global network of collaborators.

The study

In the study, the researchers suggest that together with the typical policies of birth attendance, prenatal care and the status of health services, an increase in the level of education of women reduces the probability of dying at childbirth.

“Policy papers on maternal mortality rarely suggest the lack of education as a cause for maternal mortality. Academic and public policy literature has little to say about this issue. But in Economics, there is living literature that documents a positive correlation between education and other health indicators,” Clarke says.

They analyzed cases in countries like Kenya, Nepal and Cameroon and considering the question why education reduces maternal mortality? they found that women who have received education are more likely to avoid pregnancy complications like pre-eclampsia, bleeding and infections by adopting simple and low-cost practices to maintain hygiene, reacting to symptoms like bleeding or high blood pressure and having qualified birth attendance.

Besides, women with more education are more likely to use public health services, they have delivered their children at an older age (not during adolescence) and have had less children.

These results suggest that the levels of education attained by women in any country have significant effects on maternal mortality rates.

Translated by Marcela Contreras