Académicos

Spanish

Food protective film is developed using local byproducts

Food protective film is developed using local byproducts

  • Universidad de Santiago’s interdisciplinary research team, led by Dr. Silvia Matiacevich from the Technological Faculty, is focused on developing an edible film that could increase the shelf life of fresh foods by 30%.

Improving the way of preserving foods has been a permanent concern in food industry. This is the reason why packaging is essential for the quality and shelf life of the product. But this packaging should be in harmony with the environment.

In light of this situation, a sustainable alternative for food packaging has been developed: food covering edible films, which are being widely used and have become a world trend nowadays. At Universidad de Santiago, an interdisciplinary research team is trying to replicate this development, giving value added to different national byproducts.

This initiative will be viable thanks to the Associative Dicyt Project called “Bioactive Coatings for Foods”, which gathers together experts from different faculties of the University.

“We will use food industry byproducts which are considered as dispensable or waste material. We are going to give them a value added by adding antioxidant and antimicrobial components to them in order to increase the shelf life of fresh food products,” Dr. Daniel López says.

Academics from three different faculties gathered for this purpose: Dr. Rubén Bustos, from the Faculty of Engineering (Department of Chemical Engineering); Dr. Diego Venegas and Dr. Marlén Gutiérrez, from the Faculty of Chemistry and Biology (Department of Materials Chemistry); and Dr. Daniel López and Dr. Silvia Matiacevich, from the Technological Faculty (Department of Food Science and Technology), being Dr. Matiacevich the leader of the project.

During the two years scheduled for the project, the researchers plan to study the synergistic effect of this combination of products and they expect to increase food shelf life by over 30%.

Interdisciplinarity

Most of the academics related to this project are part of a larger group created by the end of 2013 called Indi, Asociación de Investigadores por el Desarrollo e Interdisciplinariedad of Universidad de Santiago de Chile, a group of researchers that promotes development and interdisciplinarity at the university.

“All of us have participated in some of these initiatives at some point, seeking for this interdisciplinarity. This is how we have met other people and created contacts. What is good is that more than just admiring the work of others, we have the real possibility of conducting studies together. For this reason, we value this type of projects, as they promote the integration and interdisciplinarity that define a university,” Dr. Matiacevich says.

Translated by Marcela Contreras
 

Researchers share proposals for using water as a strategic resource

Researchers share proposals for using water as a strategic resource

  • Among the different speakers that took part in the Colloquium “Water: a renewable resource?”, one of them, Alfredo Zolezzi, founder of the Advanced Innovation Center, considers that the contrast between technology progress and the poverty and shortage of sanitary resources affecting millions of people is “dramatic”. He says that the solution to this problem is to make sure that innovation reaches people who need it.

The recent celebration of the World Water Day brought again to the national and international agenda the importance of promoting sustainable practices for the good use of water resources in the planet. The Colloquium “Water: a renewable resource?” was held in this context and it was led by the Association of Researchers for Development and Interdisciplinarity (INDI, its Spanish acronym), that groups researchers from the different faculties of Universidad de Santiago de Chile.

The activity brought together three speakers that approached the implications and significance of this strategic resource from very different points of view.

Leyla Noriega, journalist of Red Mi Voz*, who has experience in working with indigenous communities in the north of Chile, gave the presentation “Between the Andean world view and the community’s political core”. She explains that “our philosophy understands water like a living being. The resource is distributed according to its ancestral use by common law; that is to say, based on customs or natural rights.”

However, this expert in communications says that this approach is little respected, as a consequence of a series of processes that have affected the native peoples of the north of the country, like “Chileanization and the disassembly of ancestral authorities.”

Then, Alfredo Zolezzi, founder of the Advanced Innovation Center spoke about “Meaningful innovation”, considering it like a concept that has always been present in the history of humankind. “We have never had as much technology available as we do now, but it is dramatic to see this progress without recognizing that there are millions of people living in poverty, without basic sanitary services,” he says.

Effective solutions

In light of this situation that accounts for a complex reality, specific answers are required. According to Zolezzi, the solution lies in changing the way of doing things and he suggests “doing activism with proposals that make sure that innovation will reach people who need it.”
 
In his case, innovation became socially meaningful through the creation of the Plasma Water Sanitation System (PWSS), a water purification system that allows transforming polluted water particles into plasma, making it potable.

This system was implemented in 2011, in Fundo San José, a shanty town in Cerrillos, Santiago, thanks to a partnership with Un Techo Para Mi País**. It is worth to mention that this shanty town’s residents were resettled in June, 2013.

The last presentation was given by Dr. Silvio Montalvo, professor at the Department of Chemistry Engineering of our University, who spoke about his research regarding water resources.

At present, he is working on the treatment of sludge generated at sewage water treatment plants, in order to develop technologies to optimize the anaerobic digestion process that allows breaking down biodegradable material in the absence of oxygen.

“If we are able to preserve the water that we already have and keep it less polluted, we will be contributing to this matter,” the researcher says.

Translator’s notes: *Red Mi Voz is a digital network that promotes the practice of citizen journalism. **Un Techo Para Mi País is a nonprofit organization that mobilizes youth volunteers to fight extreme poverty in Latin America, by constructing transitional housing and implementing social inclusion programs.

Translated by Marcela Contreras

Researchers design advanced software program to detect deception through facial expressions

Researchers design advanced software program to detect deception through facial expressions

  • Dr. Edmundo Leiva, professor at the Informatics Department of Universidad de Santiago and Jorge Segura, who is pursuing a Master´s Degree in this area, developed a software program that recognizes facial microexpressions that evidence basic emotions more effectively than the human eye does. The program can detect sadness, anger and rage - that are expressed through involuntary expressions - even when they last for less than a second. According to professor Leiva, it could have multiple applications: detecting criminals at airports, selecting and recruiting staff for key positions or helping in psychological virtual therapy on Internet.

Affective computing is a research field that relates to the interpretation of human emotions through technology. It looks like science fiction, but it is more real than it appears, and our University is making progress in this matter.

Dr. Edmundo Leiva, professor at the Department of Informatics Engineering of Universidad de Santiago, together with Jorge Segura, a student at the Master’s Program of that unit, developed a software program that can identify emotions by reading human facial expressions even when someone is trying to hide them.

By means of a camera that captures facial muscles movements, it is possible to identify microexpressions, even those lasting less than a second.

“When a person is trying to deceive someone, this program recognizes his/her facial microexpressions. Microexpressions are brief facial expressions shown according to the basic emotions experienced, like anger, happiness, sadness and disgust,” professor Leiva explained.

Professor Leiva - PhD in Informatics - said that although there are experts who study and get certified in interpreting emotions through the face, their estimation range is only 63%, while “our software program has exceeded 70%.”

“Very few people are able to detect microexpressions, because an evident anger expression could hide or mask sadness, what could show for half a second. This microexpressions detector can read that emotion in a fraction of a second,” he explained.

Apps
 
Professor Leiva explained that this innovative tool has a wide scope of applications, from supporting police work to detecting the truthfulness of data provided in recruitment and selection processes of staff for key positions.

“It could be useful for detecting terrorists at airports, or even for virtual therapy given by some psychologists through Internet and Skype. The therapist could have some indications if the patient is lying or, for example, in case of senior people, if they took their medication or not,” professor Leiva said, betting that the list of possibilities could be very long. He also thinks that in the future, it could become an application for mobile devices.

“We speculate that in the future, even Google Glasses (optical displays connected to Internet networks) could have a microexpression recognition device, so that everyone would be able to detect if a person is trying to hide an underlying emotion,” he stressed.

The psychology field that related to facial expression metrics was developed by the American psychologist Paul Ekman, who is a pioneer in detecting the facial expressions of seven basic emotions considered to be linked to the atavistic part of the brain. “Sadness, anger, happiness, fear, surprise, contempt and disgust, which are emotions that all human beings show as a species heritage and not as a trait of a particular culture,” professor Leiva concluded.

The Department of Informatics Engineering is planning to show its work in this line and other research lines to the University community through different stands displaying related technology. Professor Leiva will participate to show this interesting program to anyone who is interested in knowing better about this matter.

Translated by Marcela Contreras

Industrial Engineering academics get trained in innovation at Harvard University

Industrial Engineering academics get trained in innovation at Harvard University

  • Professors Dr. Juan Sepúlveda, Dr. Astrid Oddershede and Dr. Felisa Córdova, who were invited by the International Academic Program, took part in a seminar where they acquired new tools for problem solving through creative thinking. This will considerably benefit the students and will allow improving and updating the Industrial Engineering curricula.

Between January 07th and January 09th, the academics of our University’s Department of Industrial Engineering, Dr. Juan Sepúlveda, Dr. Astrid Oddershede and Dr. Felisa Córdova were invited by the International Academic Program (IAP) to take part in the workshop “Design Thinking and Innovation” at the renowned Harvard University, USA, where they acquired tools to solve problems in an innovating and creative way. They said this will enrich the educational experience of their students.

Specifically, the seminar was given by Professor Srikant Datar to 22 academics from different Latin American universities selected by the IAP and it was held at the Innovation Laboratory of Harvard Business School

Dr. Juan Sepúlveda, the Head of our University’s Department of Industrial Engineering, claimed that this continuing education program for university teachers “is a great progress in updating our teaching methodologies and in adopting thinking and problem solving innovative techniques that we will implement in our classrooms starting this year.”

“The topic that gathered us together in this seminar- Dr. Sepúlveda explained- was ‘Design Thinking’, an approach to develop innovation that is based on the designers and architects’ point of view, which have a very different way of thinking from engineers.”

Dr. Sepúlveda added that Design Thinking is “a very useful methodology to leave behind the conventional paradigms of engineering management, and for us academics, it will be very helpful to show our students that creativity can contribute to solve a large number of problems of our professional lives.”

“After this academic experience, we look for transmitting what we learned to students, so that they dare to break the known models and seek for creative answers to the challenges that they will face in the field of management,” he pointed out.

While, Dr. Felisa Córdova agreed with Dr. Sepúlveda and said that in this visit to Harvard, “we were able to see the learning and teaching methodologies used at this renowned American university and also had access to the researches that professors are now conducting there.”

“After this seminar, the idea is to promote and develop a disruptive way of thinking among our students at Universidad de Santiago de Chile and encourage them to develop a creative thinking, so that they behave out of the ordinary, break the paradigms to implement their innovations then,” Dr Córdova said.

“In the end, this will have an impact on our students, because when they know that their professors are constantly updating their knowledge and that they are taking part in academic activities at Harvard University, for example, they feel supported by teachers of excellence, what in turn makes them more committed with their classes,” she stressed.

For his part, the Head of the Department, Dr. Sepúlveda, concluded that updating knowledge and acquiring new learning and teaching experiences that are world-wide recognized “give our institution a great boost to keep our strong commitment to continue forming world-class professionals.”

Translated by Marcela Contreras

Academic highlights the role of festivities in strengthening a nation’s identity

Academic highlights the role of festivities in strengthening a nation’s identity

  • Dr. Maximiliano Salinas, researcher at the Department of History, was invited to Universidad de Concepción’s Summer School, where he talked about the meaning of festivities as part of the historical process of a country. “During festivities, people reencounter the essence of their human, spiritual and collective experience,” he stressed.

“Celebration: Dionysus’ times come back to us” was the name of the presentation given by Dr. Maximiliano Salinas, professor at the Department of History of Universidad de Santiago, to the Universidad de Concepción’s community in the inauguration of this university’s 2014 Summer School.

On this occasion, the activity that has been carried out uninterruptedly for more than a decade, has the topic “Festivities: the art of celebrating” as its central subject, a subject to which our University’s researcher can considerably contribute, as he is an expert in popular culture history.

Regarding the role that celebrations play in local identity, the academic says that in all cultures and civilizations, festivities are an integral dimension of people’s lives, because during celebrations people reencounter the essence of their human, spiritual and collective experience.

“In the case of Chilean history, festivities, like all life dimensions, are crossed by contradictions stemming from the colonial times. Indigenous peoples were prodigiously inclined to celebrating. The colonial times order, the European enlightened absolutism, tried to control and restrain that spirit,” Dr. Salinas explained.

However, according to Dr. Salinas, that was not possible, “because the celebration legacy was passed to mestizo peoples and it got mixed with the festive influences from Spain and Africa that left us the cueca, the dance of the Chilean celebrations. Although colonial aspirations- coercive and repressive ones- are replicated until today, festivities will always represent the extension of our humanity and our spirit. The student protests nowadays have undeniably included a festive component that is part of our more permanent culture.”

When asked how the military dictatorship affected this characteristic feature of Chilean culture, Dr. Salinas said that this process can be understood as a systematic effort to extinguish the spirit of popular celebrations, indigenous or mestizo festivities in the country. “Their ambition to impose manu militari, the neoliberal discipline was, basically, an aggressive aspiration to finish with community life and the merry communal living among Chilean people. The idea was to subdue us and turn us into consumerist, scared and indebted individuals,” he said.

According to the expert, a cultural reflection about our identity as a nation is a challenge today, especially in a context in which some sectors of our society express the need of having a new Constitution. “In this sense, it is essential to have a reflection and a discussion about celebrations, as they are part of our original biological and spiritual make-up as a country. This is much more deciding, lively and deep than legal texts or the discussion among constitutional ‘experts’,” he said.

Finally, Dr. Salinas thinks that we should recover the original religious spirit of celebrations, that is to say, the spirit reflected by Dionysus, the god of cosmic harmony, of beautiful lush vegetation; the god of the joy of a nude and equal community without disguises and without ambitious aspirations. “We have to recover the spirit that indigenous peoples had and cultivated for thousand of years and that mestizo peoples legitimately inherited. In that spirit, we should find the delighting value given by the historical vindications of our societies during the 19th and 20th centuries. This was especially expressed during the Government of the Popular Unity, in a much more decisive way than in any other particular political circumstance. There it lies the deepest mysticism of festivities,” he said.

Translated by Marcela Contreras

Researcher of Faculty of Chemistry and Biology joints editorial board of renowned scientific journal

Researcher of Faculty of Chemistry and Biology joints editorial board of renowned scientific journal

  • In recognition of his extensive career in the area of electrochemistry, Dr. José Zagal, professor at the Department of Chemistry of Materials, was invited to be part of the editorial board of Electrochemistry Communications, an international journal with the higher impact index in its field.

Dr. José Zagal, professor at the Department of Chemistry of Materials of our university, was selected to be part of the editorial board of Electrochemistry Communications, the renowned scientific journal partnered with Elsevier that has the higher impact index in the field of electrochemistry.

In a conversation with UdeSantiago al Día, the academic said that he understood his inclusion in the board as “recognition of my work over many years; but most important, the recognition of a work that has mainly been done by a team.”

Professor Zagal has a vast experience in the scientific research field, particularly in the study of oxygen and reactivity. He started to work at Universidad de Santiago 40 years ago and he has kept on publishing specialized articles in his field of interest since then.

Besides, he has been part of editorial boards of different scientific journals, like the International Journal of Electrochemistry of Hindawi Publishing Corporation, since 2011 and the International Journal of Biotechnology & Biochemistry (IJBB), since 2012.

Zagal said that it is very important that both students and academics produce publications in their fields and get involved in different creative processes “to contribute not only to this University’s development but to all the country.”

“I think that it is necessary that students in any program should take part in creative and practical processes, that is to say, they should get involved in laboratory work since their first years at the university, so that they produce new knowledge that can reach most of the people through renowned publications,” he said.

“Publishing research results is essential. When you make public the work you do, your work becomes recognized in that field and, at the same time, you spread new knowledge,” he added.

For this reason, professor Zagal expects that his role at the Electrochemistry Communications’ editorial board means a contribution to the promotion of sciences and to the better positioning of Universidad de Santiago de Chile.

“You stay at this university because you love it and not for the money. Many researchers here might well be working at private sector companies, but they stay here because they feel a real bond with this institution,” he said.

“For the love that I have for this University, I expect that my inclusion in the editorial board will benefit the institution and will contribute to spread knowledge among society,” Dr. Zagal concluded.

Translated by Marcela Contreras

University of Tokyo interested in organizational analysis methodology developed by Department of Industrial Engineering

University of Tokyo interested in organizational analysis methodology developed by Department of Industrial Engineering

  • Professor Osvaldo García was invited to give a presentation on an organizational self-observation tool, called CLEHES©, to postdoctoral students of Takashi Ikegami Laboratory, an institution specialized in the field of artificial life, at University of Tokyo.

More than ten years ago, Osvaldo García, professor at the Department of Industrial Engineering of Universidad de Santiago, started to develop CLEHES, a tool that intends the individual to generate learning, both at a personal level and at workl, through self-observation and the observation of interactions among human beings and their constituting networks, developing a diagnosis and an organizational design through Body, Language, Emotion, History, Eros and Silence (CLEHES©, its acronym in Spanish).

The contribution made by the course given by professor García, called Human Reengineering for Action (Rihpla, its acronym in Spanish), of the Department of Industrial Engineering, together with the academic prominence and prestige of CLEHES, made the publication of this innovative tool to be among the 100 most important international scientific publications in the field. In turn, it called the attention of different institutions that were interested in this emerging and effective technology.

For this reason, the professor Takashi Ikegami´s artificial life laboratory at the renowned University of Tokyo, in Japan, contacted professor García and invited him to give a presentation in September 2013 to graduate students at that Asian institution.

Professor García explained that, at Takashi Ikegami Laboratory, where the latest advances in robotics are being developed, they had a closed seminar for postdoctoral students and, besides, they explored the applications of CLEHES to the field of artificial life.”

“Students there made an effort to evaluate what changes could be made to apply some aspects of CLEHES´ structural dynamics to robot building,” García said. “We even talked about the possibility of generating a CLEHES-Robotics tool in collaboration with our University,” he added.

Professor García, an academic at Universidad de Santiago, stressed that, in Japan, robot building “is not approached through aggressive or merely recreational policies. It is considered a contribution to society, for example, to help senior citizens.” Therefore, the social self-observation tool CLEHES would be very useful.

Professor García showed himself satisfied with the new possibilities of internationalization and collaborative work with Japanese specialists opened by the research during the Rihpla course and CLEHES, and besides, he highlighted the concept of applied “ortho-discipline”, that is to say, to respect the autonomy of the different specialists involved in a collaborative project.

“In the Japanese culture, it takes time to establish collaborative relationships, but even so, we were able to forge significant links with them and also with the Japanese Embassy, where entrepreneurship and innovation are developing valuable bilateral ties,” professor García concluded.

CLEHES used by young researchers

Susana Gómez, who is doing her dissertation on diagnosis for her Master´s degree in Engineering Sciences using CLEHES technology, said that this innovative tool has been very useful to young students who pursue a specialization in management solutions.

“The networks created due to the international prominence of CLEHES have been amazing,” she said.

“This is a really new tool for management that is gaining strength and is being put into practice. Japanese specialists have the theoretical knowledge and the laboratories, but they have not put this technology into practice. Here in Chile, we have taken it to companies and schools and we have also applied it in our academic unit both in undergraduate and graduate students,” she said

For his part, Roberto Álvarez, a student who obtained his Master´s degree in Engineering Sciences by doing his dissertation using CLEHES to solve organizational problems said: “This management tool has been very helpful for my professional career and for working at big companies.”

“Besides, studying and applying this meta-discipline has helped us to open opportunities and to differentiate ourselves from other universities’ students,” he concluded.

Translated by Marcela Contreras

University will offer B-Learning English courses for all undergraduate programs

University will offer B-Learning English courses for all undergraduate programs

  • The Academic Vice President, Fernanda Kri, said that after testing the pilot program in more than a thousand students of the Faculty of Engineering, the system that combines on-line learning opportunities with face-to-face sessions, proved to work in a similar way to a traditional course. “The goal is to implement this system for all our undergraduate programs in the first semester 2014, according to our Institutional Strategic Plan, which stipulates the promotion of the English language among our students,” Vice President Kri said.

In April this year, our University’s Academic Vice Presidency, together with the Consejo Superior de Docencia (the consulting body to the Academic Vice Presidency) and the Educational Innovation Unit started implementing an English language B-Learning pilot program for students of the Faculty of Engineering in order to evaluate the system’s operation and extend its application to other undergraduate programs of Universidad de Santiago.

The B-Learning method combines on-line content delivery with face-to-face sessions. It was implemented with the support of our University’s Department of Linguistics and Literature for one thousand and fifty students during one semester.

After concluding this first evaluation stage, the results proved to be very positive; hence, the academic authority started promoting its implementation in all undergraduate programs, according to one of the goals of the Institutional Strategic Plan, which stipulates the promotion of the English language among the students.

On November 27th, the Academic Vice President, Fernanda Kri, had a meeting with the academic community to inform about the results of this first B-Learning experience. She described it as “successful”, both logistically and academically.

“We confirmed that students who participated in B-Learning lessons acquired and English language knowledge similar to the one acquired in one semester of face-to-face sessions,” she said.

Due to this positive evaluation, the Academic Vice President invited all undergraduate programs to be part of the initiative.

“The purpose of the meeting (held on November 27th) was to show these results to the different faculties, hoping that most of them will join in this project and include it formally in the programs’ curricula as of March 2014,” she said.

“We expect all students at the University reach at least an intermediate level of English and for that to happen, they need to take four consecutive English courses, lasting one semester each, as this is the only way of having continuity in learning,” she added.

Vice President Kri concluded by saying that, besides the good results, “Students showed themselves very motivated for using technological tools and for learning English early in their programs. All this gives us good expectations about the contribution that this project may be to our community once it is extended to all undergraduate programs and, in the future, to graduate programs.”
 
The details about a successful program

Ricardo Úbeda, professor at the Department of Linguistics and Literature, who is in charge of the program, informed that out of one thousand and fifty students who took the B-Learning course, 182 passed the initial diagnostic test and were exempt from the final test, while 744 students totally passed the course.

Another announcement was the implementation of more mechanisms to allow the interaction between students and teachers, like Skype, that can help to solve questions in a direct way.

“Finally, with this course, all our expectations were met and we were able to see the high level of commitment that the students of our University have with their integral learning process,” professor Úbeda stressed during the presentation of the results of this B-Learning system.


Translated by Marcela Contreras.

Research will study flotation process to recover copper

Research will study flotation process to recover copper

  • The research, led by Dr. Miguel Maldonado, professor at the Metallurgical Engineering Department, intends to optimize this process through new on-line air measurement equipment.

During the last couple of years, we have heard about a decline in copper production, and according to experts this is one of the reasons why the quality of the mineral has been reduced. One way to revert this situation is improving mining procedures, which is a priority for mining industry.

One of these processes is flotation, a method used to separate valuable minerals like copper from others. The process starts once the rock is ground and mixed with water to form a pulp. Some reagents that modify the mineral surface are added to this mixture. In this way, when bubbles of air are forced up through the pulp, they collide with particles and the ones containing copper, for example, go up to the surface making a froth rich in valuable mineral, ready to be removed.

This is the method studied by Dr. Miguel Maldonado, professor at the Metallurgical Engineering Department. “Although today improvements have been made to flotation process- by means of devices that measure the air flow forced into a flotation equipment or the use of cameras that continuously monitor de physical properties of the froth- we still do not have a full knowledge of how air dispersion in the bubbles affects the metallurgical performance of the process,” the researcher said.

This encouraged the academic to do a research project called “Estimating on-line air concentration in flotation systems,” funded by the Scientific and Technological Research Department (Dicyt) of Universidad de Santiago.

“We believe that this variable is important when determining the process performance, as it is related to the surface area available to collect the particles containing valuable mineral and, therefore, to the complete recovery of copper,” the researcher explained.

The researcher said that the project was born while he was doing his postdoctoral research in Canada, at McGill University, considered a pioneer institution in proposing ways of measuring this variable. At that time, while he was studying this technique, he found out a problem with the interpretation of Maxwell’s equation, which would lead to a measurement error.

For this reason, the academic decided to insist on seeking new techniques in order to solve the problem; this time, with a better knowledge of the system.

At the first stage of the research, essential aspects of the error made will be studied. For this purpose, experiments to get a better understanding of the Maxwell’s equation will be performed. McGill University will also take part in this research by sending a flotation column to support the study and by developing papers together about this topic.

At the second stage, new techniques will be explored to find a method that estimates the air concentration in real time, in order to control and optimize the process.

In the academic’s opinion, “the efficient recovery of valuable minerals like copper is very important, and this measurement method could provide significant information for optimizing the process. This will have all kinds of benefits, such as reducing the reagents added or reducing the water used. This fact is also important if we consider that in most mining operations the water resource is scarce.”

 

Translated by Marcela Contreras

Academic studies brain development process in human embryos

Academic studies brain development process in human embryos

Providing basic knowledge about human cerebral cortex development at embryonic and early fetal stage is the goal of the research project led by Dr. Lorena Sulz, which will be conducted during the next three years.

According to reports, some psychiatric disorders, such as schizophrenia and bipolar disorder, begin during embryonic development. Most of the studies on this topic have been conducted on animal samples, due to ethical restraints and limited access to human embryos. This is the reason why the field of human embryology related to neurology is an area which has not been thoroughly explored.

In this context, Dr. Lorena Sulz, academic of Universidad de Santiago’s School of Medicine, will carry out the study “Role of nitric oxide in human cerebral cortex morphogenesis”, which intends to gather critical information about the mechanisms involved in the development of nerve cells during the first weeks of pregnancy.

The study will be conducted during the next three years and is funded by the Scientific and Technological Research Department (Dicyt) of Universidad de Santiago. It is a unique study as it is the first time that this branch of embryology involves human samples, which were obtained from de Institution’s Embryo-Fetology collection.

The idea is to gather basic knowledge about this topic in order to explain if the presence of nitric oxide is also essential for producing new nerve cells in human cortex, as it has already been proved in animal samples and in neuronal regeneration processes, both in human beings and mice. “We want to know if this molecule is expressed in the cerebral cortex being developed and identify in what areas and at what stages it is present. In this way, we can infer approximately the process in which it is involved,” the academic explains.

The study will be carried out in two stages. The first one will completely focus on the morphological analysis of cells and embryos being used. This stage, which is under execution at this moment, will allow describing the human cerebral cortex development process. After identifying each phase, the second stage will allow identifying cells that produce nitric oxide and the process in which it would be involved.

The study will be conducted at the Embryology Unit of the Faculty of Medical Sciences, Universidad de Santiago, led by Dr. Jaime Pereda, the project`s co-investigator, M.S. Carlos Godoy and Dr. Sulz. The three professionals, experts in their areas of research interest, complement each other’s work in a way that has helped to a good execution of their projects. “In general, the three of us work together because we use very similar techniques: only the molecule and the body organ of interest are different. We have adjusted to each other very well,” Dr. Sulz adds.

However, the expectations are long-term. The research seeks to establish some theoretical basis for human cerebral cortex development, in order to develop new studies on this topic. The results will be presented in different papers in specialized publications and in different congresses and conferences.

Finally, Dr. Lorena Sulz expects that during the research, they will be able to prove that nitric oxide takes part in human cerebral cortex development, just like it does in laboratory animals. “As it is basic science, it only provides a knowledge base. But if nitric oxide is known to be significant in cerebral cortex development, further care should be taken so as not to interrupt this process during the critical period, preventing potential malformations. This additional knowledge could be a contribution to prenatal care,” the researcher concludes.

Translated by Marcela Contreras

Pages

Subscribe to RSS - Académicos